Wednesday, 12 December 2012

Stem Cells in Health and Disease

Dr Rahul Naithani

Stem cells are basic naïve cells present in all humans and have the ability to become any type of cell to form skin, bones, organs or other body parts. We all get injuries in our growth years and otherwise. It seems  surprising how our wounds heal and new skin comes up. This is largely because of a pool of cells in our body called stem cells.

Different organs of body have their own stem cell pool. There are different types of stem cells. Theoretically, some of them can regenerate any kind of body tissue. Stem Cells have been responsible  for our recovery from different traumas that body organs face. There is great interest in the ability of stem cells to treat neurological ststes like multiple sclerosis. There are situations where a person’s own stem cells may be used. In genetic conditions, a different healthy person is required to donate stem cells which help regenerate blood forming cells in a patient. Clinically, stem cells are used in the treatment of several of hematological diseases like blood cancer, thalassemia, aplastic anemia, etc. Intense research is on  to find if stem cells can be used to regenerate all tissues of body. As of now, the only clinical usageis in bone marrow transplants. Stem cell therapy has also been useful in autoimmune diseases. A good source of stem cells is cord blood stem mcells which can be stored at birth. These cells are generally helpful for other people and not the same person whose cells are stored.

Since  theses cells are naïve, there may be a future role of stem cells as therapeutic drug delivery molecules. At the same time there are lot of myths and misconceptions about the immediate use of stem cells. These should be clarified with an expert.

The author is Consultant –in – charge, Bone Marrow Transplantation & Hematology, Max Cancer Centre, Max Super Specialty Hospital, Patparganj.

Thanks

Max Health Line,

21/10/2012

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